Big military undergraduate's thesis is issued in Japan " cancer science " online

Big military undergraduate's thesis is issued in Japan " cancer science " online
Big military undergraduate's thesis is issued in Japan " cancer science " online
The reporter Jiang Ming learns from Wuhan University basic medical college on March 31, this institute four grade undergraduate great to receive the intersection of Japan and cancer learn official periodical " cancer science " (SCI periodical) just Wang Zhi have The notice of the editorial department, study the thesis <>Have already issued online. Previous research verifies, " the the member police " P53 restrains one of the cancer genes importantly, it may cause the emergence of cancer that mutation takes place or lack in p53 gene, and the more MDM2 albumen is, it is the apter to cause p53 gene mutation or lack. Arrogant to study second grade, begin ZhiHao Wang, spend time enter the neurological laboratory of member make scientific researches after school, the relevance engaged in Pirh2 albumen and tumour is studied. He finds under study for action, in cases some is unusual, when DNA damages, MDM2 can not degrade p53 gene effectively, and Pirh2 15 the intersection of serine and the intersection of phosphorylation and activatory p53 suffused with usually melting and degrading can damage DNA, Pirh2 in many kinds of and p53 getting wild to express competence to be relatively high in the the intersection of cancer and the intersection of cell and department with sudden change type at the same time. The larger the content of saying popularly it is Pirh2 is, it is the apter to cause reproduction and growth of tumour cells, so he thinks Pirh2 albumen has already broken away from MDM2 albumen " Black " The ring of light, " accomplice " having illness coming on as human cancer . According to the introduction of Wang Zhi great counselor associate professor Liu WanHong and Professor He XiaoHua, this first adjust and control cell, proliferate split up, the intersection of albumen and the intersection of person who secrete and the intersection of function and article that system expound the fact to the intersection of Pirh2 and albumen at present, this article at the same time has carried on the function that Pirh2 albumen is potential relevantly to sum up and analyze too, infer it may one new carcinogenic albumen, this pair launch pathogenic mechanism of tumour and treat research that target order, have important directive significance thoroughly further. Usually, generally inviting of the editor directly or after the strict qualification is examined expert writes the academic research progress in this field in the summarizing thesis, it influence factor to be relatively high, article relatively difficult to deliver.


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