Find that there are reliable methods to send the natural selection newly

Find that there are reliable methods to send the natural selection newly
Find that there are reliable methods to send the natural selection newly
Shanghai, August 31 (Xinhua) ' The reporter wins honour for) How to measure the natural selection taking place recently reliably? The reporter calculates the biological research institute to know from the research institute of Shanghai life of Chinese Academy of Sciences on August 31, researcher Li HaiPeng's latest research results, the dream over the past 20 years of colony's hereditary educational circles of this theory of round. Researchers introduce, in evolution of the life, the natural selection is a kind of important evolution strength, it make carry individual of sudden change a certain to carry the individual of sudden change, come, say, have, survive and breed advantage that pay. It is not merely playing an important role in wild colony and modern and human evolution, and grow the animals and plants at home ' Such as rice, dog and pig) Cultivation and domestication course hit play a decisive role. Through keep in the intersection of organism and genome about the intersection of natural selection and incident " The clues " ,We can study the function of the gene mutation, and explore the basic secret of evolving finally - -Molecular biology mechanism of the adaptability evolution. When measuring natural selection incident at present, a key research obstacle lies in, need to estimate the change of colony's quantity in the long-term evolution course of the research object in advance, in order to improve the credibility that the natural selection examines. However, even adopt the present analytical method of many attitude data of heredity at the genome level, still it is difficult to estimate the concrete false positive rate in the analytic process accurately, therefore the accuracy just difficult to improve relevant research. Over 20 years in the past, a main goal of studying in science of heredity of theory colony, an effectual method that just set up, make measure the influence that the natural selection taking place recently is not changed by colony's quantity. Li HaiPeng's research results have turned this dream into reality. It is introduced, Li HaiPeng has put forward a kind of brand-new natural selection measured and taken place recently through the topological structural tactics of examining the tree, and set up corresponding statistics method. Two respects of mathematics and computer simulation prove, this statistics supposes the result examined is free of colony's historical quantity change. This means no matter how the quantity of the colony in history changes, the false positive rate of this new method will keep under significance levels had when it is examined that statistics is supposed. Moreover, the new method does not need information of history of any population or estimation to population's parameter, do not need many attitude data of heredity of the genome level either, only need coming from many attitude data of heredity of a bit of DNA, can measure the natural selection taking place recently reliably. At present, it is influencing the factor as MBE (MolecularBiologyandEvolution) of 9.872 that this research results have already been issued On the magazine.


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