The crowd of the Han nationality studies and makes progress in hereditary structure

The crowd of the Han nationality studies and makes progress in hereditary structure
The crowd of the Han nationality studies and makes progress in hereditary structure
It is reported ' Reporter Li TianShu) Recently, the Chinese Academy of Sciences releases news to point out, magazine of " human science of heredity in U.S.A. " has issued the research institute of Shanghai life of the Chinese Academy of Sciences and calculated the heredity of biological relevant crowds of the Han nationality of gold strength seminar of research institute online Research results of the structure. The research passes the analysis to the whole genome data of more than 1700 the Hans, the research has not merely announced the crowd of the Han nationality of Chinese has differences between the south and the north, still quantized the hereditary difference of different crowds of the Han nationality in all parts at the same time. The Han nationality of China is a nationality with the largest population, account for 20%, 92% of China's population of world population. The related research of the whole genome is the effective searching malignant tumour most that scientific circles is generally acknowledged at present, exchange the research approach of the sense gene in great diseases such as schizophrenia, hypertension, diabetes,etc.. With high the intersection of flux and the intersection of chip and becoming ripe technology of dividing etc., the whole the intersection of genome and related research become complicated the intersection of disease and a daily means that gene orientate at present gradually already, already relevant research results of related research of nearly 400 items of the whole genome are issued so far. However, the related research of the whole genome faces the false positive result problem that crowd's hereditary structure causes all the time. The crowd of the Han nationality has a long history, the forming of the Han nationality is that a multi-national colony contacts, exchanges, binds and the complicated course of integration. Segregation, integration and migrating at various degrees of several thousand years, will cause the hereditary difference between the colonies of the Han nationality of different areas inevitably. So, analyze the hereditary structure of the crowd of the Han nationality, quantize the hereditary difference of the crowd of every area the Han nationality in an all-round way, and fully find out about the influence degree to related research of the whole genome of the hereditary structure of the crowd of the Han nationality, it is a prerequisite of rational experimental design, guarantee the requirement that the related result of study of the whole genome is reliable too. Researchers pass the analysis to the whole genome data of 26 more than 1700 the Hans of province and city in China, having announced that there are differences between the south and the north at the hereditary level of the Han nationality of China, portrayed the hereditary structure of the crowd of the Han nationality at the same time, it has been calculated differently and sampled the possibility of false positive result and size of the statistics efficiency in the tactics and studied through computer simulation.


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