Chromatin is reinvented unusually or causes bladder cancer

Chromatin is reinvented unusually or causes bladder cancer
Chromatin is reinvented unusually or causes bladder cancer
It is reported ' The easy reporter of reporter Lee's weather Liu Jia) A few days ago, discover by the intersection of Peking University and the intersection of Shenzhen and hospital and the intersection of China and old the intersection of genetic research institute and one that finish jointly, chromatin reinvent might lead to the fact the intersection of bladder and an important reason that cancer take place while being unusual, this, for diagnosis, treating and establishing the foundation of science of heredity of bladder cancer. Thesis of this research is published in " natural science of heredity " recently. It is introduced, it is that the apparent heredity decorates a kind of important mechanism in the mode that chromatin is reinvented, the unusual normal expression that will all influence the gene takes place in any link among them, thus cause a lot of complicated diseases. If mutation causes and restrains the cancer gene or regulates the albumen of cycle of cell to become abnormal, may cause emergence and development of cancer. Researcher move cell cancer of the conduct to 9 bladders ' Most common type in bladder cancer) Patient sample carry on genomics analyze and check order, find 54 and bladder move the intersection of conduct and cell cancer happen relevant prominent the intersection of mutation and gene, among them 8 reinvent the relevant mutation gene and is found with chromatin, 7 mutation genes are found in the bladder move cell cancer of the conduct for the first time. Subsequently, this result has proved in 88 bladders moved the sample of cell cancer patient of the conduct. In 97 bladders move the sample of cell cancer patient of the conduct, the mutation of body cell has taken place to have chromatin of 59% of the patients to reinvent the relevant gene, therefore researchers infer it may be one of the important mechanisms of leading to the fact the bladder moves cell cancer of the conduct and takes place and develops that chromatin is reinvented unusually.


|