Thursday, August 30, 2012

The soup encourages You: Confirm the scientific research direction is the most important

The soup encourages You: Confirm the scientific research direction is the most important
The soup encourages You: Confirm the scientific research direction is the most important
As to the tumour treatment, the soup encourages academician You to think, it can not only stay in SCI article and patent are declared to give play to the clinical advantage. There should consummate technology that will also have a biological idea, excise tumour as well as keep the organism. And all these, depend on the broad thinking of scientific research. Emphasize " Get twice the result with half the effort " Prevent and cure and study tumour of the distinct Chinese characteristics, three are very important that have. First, put prevention first. Second, examine and manage early early. Though examine, manage, have a history of 30 years already early early, 30 the next might be but also the most important route to raise curative effect in year. Third, make sure " productive, efficient, high-class and economical " Cure the disease. Some therapeutic method now of ours is good, but a lot of persons can not afford to use, easy popularization. In the seventies of last century, formed tumour with Chinese characteristics and prevented and cured and studied the frame slowly, have occupied a tiny space in world for the first time. It special has three points to sum up: Find out the morbidity of the main cancer of our country, cause of disease, is distributed tentatively; Have taken shape " Three is early " The characteristic, especially hepatocarcinoma, cancer of the esophagus, nasopharyngeal carcinoma; Have shown the foundation, clinic and scene " Combine by three-in-one " Experience. In 1979, I published " analysis of 30 of small hepatocarcinoma ". At that time it realize this pieces of article is for distinct Chinese characteristics, shortly after get we by gold medal of U.S.A.. International modern hepatopathy study the intersection of founder and HansPopper, write the preface for " inferior clinical hepatocarcinoma " that me edit once. He wrote, inferior clinical hepatocarcinoma, this concept, was that the mankind knew and treated the great progress of hepatocarcinoma. See later now why small hepatocarcinoma has already been approved by world in the past 30 years till now, I want to accord with " Productive, efficient, high-class and economical " This principle. This will be still emphasized today. Whole views and individuals combine and prevent and cure the research to hepatocarcinoma of the distinct Chinese characteristics, I think that there are several that are worth paying attention to. Study and is directed against the most essential treatment of cancer in article 1. Cancer should be shifted, so should study and shift. Article 2 is the individual, individualized treatment. Reflect it is very important that the individual of the whole view treats. Because so-called individual treat now, a lot of the intersection of molecule and target, to treat, to some one or several target of molecule to treat in fact, the ones that have totally avoided the whole are changeable. If can combine macroscopical level, integral level with the molecule level, micro level, the individual will treat more complete. Three transfer, cancer and transfer to the organism ' Including microenvironment) It is the complex treatment of the focal point. Regarded eliminating cancer as the complex treatment of focal point in the past, should add and adjust and change cancer, adjusts and turns into the complex treatment of the organism now. Fourth, should recommend changing some concrete methods excessively diagnosed, excessively treated. To cancer essence and research of shifting, it is very difficult brainstorm subject. The thinking should be wide at first, can't only consider cancer, will consider the microenvironment, in view of the human body. Maximize favourable factors and minimize unfavourable ones, develop the clinical advantage. Secondly, emphasize the individual of the whole view treats. The whole view of Chinese medicine has a history of more than 2000 years, it constructs the thought managed dialectically and very worthes our paying attention to. Third, pay attention to the change of the medical mode, many places that is worth drawing lessons from of traditional Chinese medicine. When I have just studied hepatocarcinoma in the seventies of last century, the traditional Chinese medicine clearing away heat and detoxifying with a lot of half a piece of lotuses, snake's tongue grasses,etc., a result was not given up at that time. Have never expected the relation of inflammation and cancer caused the attention in whole world recently, the result of resisting the inflammation treatment and improving cancer has already been got definitely. On the contrary, clearing away heat in Traditional Chinese medicine has its scientific reasons to detoxify. If these things can continue developing, may accomplish the less, effectual expenses. Put emphasis on adjusting and changing cancer and adjusted and turned the complex treatment that is combined into the organism, had not denied and eliminated the method that tumour used having an operation, radiotherapy, chemotherapy in the past. Eliminate tumour to remain mainly, basically, but not solved the incomplete cancer slipping through the net on this basis, the patient will also die because of recuring, shifting in tumour finally, so should change the strategic principles. It should confirm the scientific research direction first and should pay attention to three respects to form the characteristic. The first is a demand of the country. The second is studies the mainstream should belong to this discipline of the direction, and should consider the front of discipline, the discipline direction be able to drive the overall situation, improve curative effect. Form the characteristic, the scientific research direction that must be steady. Third, fix the scientific research direction and need the strategy eyes, need wider range of knowlege, understand the latest information of the scientific and technological tendency, there is choice ability. Go over, slice, diagnose hepatocarcinoma through pathology, try every possible means with have an operation, the intersection of part and the intersection of person who treat, get involved and means eliminate the cancer cell. See total survival rate now. From the viewpoint of modern molecular biology, have already grown from single molecular biology to systematic biology slowly, from only studying a gene to study all genes and proteins in all cells. In addition, also need to summarize the experience and discovering the problems constantly. Our research institute finds through studying the impatient's survival rate in the past few decades, original gentleman very low person who deposit have, the next 10 years raise, raise even in 10 later on and then, but not improved too greatly for most recent 10 years, 20. Why? Because has not solved the problem of the metastasis of cancer. Would not find this question without summarizing. This is the reason why why we changed a scientific research direction every 10 years in the past. The first scientific research direction is to study and find in early days, diagnose, treat in early days in early days. Found later, although the early patient had solutions, the big hepatocarcinoma met has no solution every day, transfer the focal point to using comprehensive treatment means second 10 year, turn big hepatocarcinoma into little hepatocarcinoma, thus excise it. Third stage, whom everybody find no matter light hepatocarcinoma excise and big hepatocarcinoma excise, recur excision or 2 steps are excised and then, meet quite high recuring rate of transformation. This problem is not solved, it is very difficult to further improve. So 15 years ago, we transfer the whole research direction to the transformation which studied hepatocarcinoma and recur. In 1993, everybody made very difficult resolution: Study target for 13 year to treat, give up all, change get transformation to study hepatocarcinoma in the past. Have a look later now, fortunately there was this resolution at that time. Do some things, leave some things undone, through efforts of several decades, obtain the First Prize of Progress in National Science and Technology, and caught up with the international trend. It is a goal that reference the means innovates to innovate to form the most important core of the characteristic. The first should have innovative consciousness. If you are awfully busy, do seven or eight operations each day, but there is no innovative consciousness, busy can only remain at this level all one's life. The second should have dialectical thinking, dare to revise those routine, law of the past. Third should have daring and resolution and willpower ,Dare to take risks and persevere, calm in the face of failing. The fourth should have clear goals. Do we cross? ? Having transferred to three directions in 0, the goal is for improving curative effect, create the characteristic. The most important one is the dialectical thinking, especially reverse thinking in the soft capability. We will recommend the skillful capability, will turn some research results into the clinical and useful thing in time. Any make a diagnosis method relative, adapt to a certain period only, a certain particular target is not correct forever. So long as find the thing with better more method than existing making a diagnosis, is worth transforming. Reference is a means, it is a goal to innovate. We can't remain in foreign competence of following closely, and forget to creat the goal with Chinese characteristics. Scientific research is a foundation, it is a goal to transform. We should maximize favourable factors and minimize unfavourable ones, give play to the clinical advantage, can not only stay in SCI, stay in the declaration of the patent. If we have consummate technology and also have a biological idea, especially have organic conceptions, excise tumour as well as keep the organism, eliminate tumour as well as adjust and turn into incomplete cancer, we will have a broader thinking. There is an article that calls " fierce competition of thinking between east and west " in the East in " Reference News " recently different from western thinking. I especially appreciate inside one sentence is analyzed: Orientals are inclined to whole thinking even more, and westerners are good at analyzing. If nobody has grasped the strong point of two kinds of world outlook between east and west, who can obtain the greatest success in the 21st century. This gives us some thinking in terms of macroscopic. Really western thinking is to clarify mechanism first and then design how to treat, and the thinking in the East is to practise clarify mechanism effectively first and then, treat hepatocarcinoma, treat leukemia, just affirm after curative effect like Arsenicum, and then go to clarify scientific mechanism, issue on SCI. The thinking in the East can often be found from the chance inevitably. I find that there are many desirable things to recover inside the club in cancer now, because it is all very optimistic to participate in most of patients of cancer of the club, very willing to participate in some activities. Why on earth make these patients live long? There is no too much scientific research now. I insist on swimming after having several patients operations. Intervention that swimming is full-length? Some things can well from getting endogenous to come on perhaps, we might not want, play interferon, can produce much interferon through depending on oneself by other ways of swimming etc.. Original my maxim is " Take a broad view of the world " ,There was not reform and opening-up at that time, it was unable to go to the world. The reform and opening-up now, everybody can move towards the world too, this places hope on your young scholar. " keep forging ahead rigorously, take a broad view of the world, work with perseverance, rejuvenate China " ,Put forward and mutually encourage with everybody.


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