It can be safe and more effective to treat chronic marrow leukemia

It can be safe and more effective to treat chronic marrow leukemia
It can be safe and more effective to treat chronic marrow leukemia
It can be safe and more effective to treat chronic marrow leukemia
It is reported ' Reporter Wang XueFei) From December 4 to 7, the 52nd U.S.A. blood disease learn annual meeting hold in city, Orlando of state, Florida of U.S.A.. A global clinical research of random, open, many centre - -ENESTnd result of study announced at the meeting: The data for 24 months reveal, reach and wish to receive (the Buddhist nun Lip river takes the place of the Buddhist nun) Used for treating chronic marrow leukemia (CML) Security and validity last Wei ( The horse of Iraq takes the place of the Buddhist nun) . It is introduced, CML is that a kind of organism produced disease that the carcinogenic leucocyte causes. Nearly all CML patients have chromosome of unusual Philadelphia, this chromosome can turn into protein Bcr-Abl causing the malignant leucocyte to spread. CML patient accounts for 10%~15% in the adult leukemia patient. At present, it is that a gleam of which treats this disease uses medicine that it is defended that dose is listed. It is first two kinds initial and therapeutic to used in CMLing that ENESTnd studies to take large-scale clinical controlled studies that are paid and compared at random of therapeutic medicine orally. This research is implemented in 217 research centers of the whole world, is selected 846 patients together, include 117 Chinese patients. The patient is divided into accepting Damien wishes to receive and treats the group and accept at random, main research learns to react (MMR) for the main molecule when use medicine to 12 months terminal ,Lasting MMR in the terminal of secondary research is in order to use medicine to 24 months. The result of study reveals, compared with the situation that dose lists and defends and treats the group, reach and wish to receive and treat group's patient and develop to accelerate one and urgent probability which change one is lower, appear good curative effect ' With MMR in order to judge the standard is weighed) It is lower too with treating the incidence failing. Compared with the situation that dose lists and defends treating, reach, wish, receive, treat, can get lasting MMR, reach dark complete member of intensity, learn to react (CMR, namely the small remaining amount of Bcr-Abl protein is 0.0032%) . It is accepted that Damien wishes to receive the person who reaches CMR of the patient who treats accepts Georgia lists 3 times which defends patient treating. Under study for action, compared with the situation that it is accepted that Georgia lists to defend the patient who treats, it is accepted that Damien wishes to receive in the patient who treats, less patients stop treating because of bad incident.



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