Saturday, October 27, 2012

Managing the neonatal continuation lung artery has a new thinking under high pressure

Managing the neonatal continuation lung artery has a new thinking under high pressure
Managing the neonatal continuation lung artery has a new thinking under high pressure
Managing the neonatal continuation lung artery has a new thinking under high pressure
It is reported ' The reporter reporter Wang XueFei and Song Li wins) The neonatal continuation lung artery is shown as whole body is livid purple and breathes and increases symptom fast,etc. under high pressure, mortality and complication incidence are high, it has been the focus of medical research all the time. The national neonate of Society of Pediatrics studies group's group leader, research that the group that the subsidiary children's hospital Du LiZhong, Xu XueFeng,etc. of medical college of Zhejiang University make up passes more than two years, utilize animal's model, has announced the function in the neonatal continuation lung artery takes place under high pressure of apparent hereditary mechanism for the first time. Relevant theses were published on international authoritative publications such as " hypertension magazine ", " research of hypertension ",etc. in succession recently. Apparent heredity, mean besides DNA and RNA array in the genome, and other adjustment genetic information methods, these methods will not change the array of the gene, but through decorating gene, controlling function and characteristic of gene, protein,etc., and influence the phenomenon of the genetic change through cell cycle and appreciation cycle. The thinking of research is to attempt to proceed with gene expression course of the upper reaches if Du is which sets up medium-sized people, understand the apparent hereditary information of the relevant gene, hope to pass and adjust and control these links, achieve the goal of preventing and treating disease. They find, mother, the influence in factors such as oxygen deficiency, using antiinflammatory agent,etc. when being pregnant, can cause apparent heredity of foetus' relevant gene to change, cause the emergence of disease finally. Du LiZhong is explained, if liken the human gene to " password " ,Then, it " encrypts " "information text" Can not change. But the researcher finds, besides gene sequence, it seems that there are the expressions of other factor influence genes, the function that and these factors play, often have nothing in common with each other because of environment, the individual's difference. Under what kind of situation do these factors work? How greatly to influence? Content that will study in epigenetics that these are. The apparent hereditary course is reversible. The most ideal state is intervening and treating in earlier stage, entrust the gene a pair of " insight " on this basis ,Resist the invasion of disease by oneself.



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